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The Role of PKR/eIF2α Signaling Pathway in Prognosis of Non-Small Cell Lung Cancer

Figure 3

The prognostic significance assessed by using Kaplan-Meier survival estimates and long-rank test.

A–F. Kaplan-Meier survival curves according to the differences in (A, B, C) p-PKR and (D, E, F) p-eIF2-α expression in patients with stage I (A, D), stages II–IV (B, E) and all stage (C, F) NSCLC. The survival rates were significantly worse in the patients with low p-PKR or p-eIF2α expression than in those with high p-PKR or p-eIF2α expression (Stage I: p = 0.01 and p = 0.02; All stages: p = 0.03 and p = 0.03, respectively).

Figure 3

doi: https://doi.org/10.1371/journal.pone.0024855.g003