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Broad-Spectrum Antiviral Therapeutics

Figure 6

DRACOs were effective against murine adenovirus in L929 cells.

(A) 100 nM DRACOs were effective against 50 pfu/well murine adenovirus, whereas all negative controls were not (16 dpi). (B) 100 nM PTD-PKR-Apaf DRACO was effective if added before or up to at least 72 hours after adenovirus (16 dpi). (C) Multiple 100 nM DRACOs were effective against 50 pfu/well murine adenovirus (11 dpi). Even better performance of these alternate DRACOs might be achieved with further optimization.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0022572.g006