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Broad-Spectrum Antiviral Therapeutics

Figure 3

DRACOs mediated apoptosis in cells containing dsRNA.

L929 cells transfected with both DRACO and poly(I)∶poly(C) dsRNA exhibited apoptosis within 24 hours, whereas cells that received only DRACO did not. Caspase inhibitors eliminated DRACO-mediated apoptosis in the presence of dsRNA.

Figure 3