Identification of the Pangenome and Its Components in 14 Distinct Aggregatibacter actinomycetemcomitans Strains by Comparative Genomic Analysis
Genes were classified by the COG super-functional category (A) and the COG functional category (B). As expected, the core genome is better represented by genes that provide the essential cell function for the bacterium whereas the vast majority of the variable genome is made up of poorly characterized genes. Poorly characterized genes also represented about one third of the core genome. This suggests that more studies are still needed to understand the basic biology of this bacterial species.