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Conditional Random Fields for Fast, Large-Scale Genome-Wide Association Studies

Figure 2

P-value histograms for the GAW14 dataset.

a),b) Histograms of p-values obtained from our method for the synthetic (a) and real (b) GAW14 data. For comparison, p-values obtained from a logistic regression that does not account for confounding factors and from Eigenstrat [4] are shown for synthetic (c,e) and real (d,f) GAW14 data. Dotted red lines indicate the expected histogram for the uniform distribution under the null hypothesis .

Figure 2

doi: https://doi.org/10.1371/journal.pone.0021591.g002