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Predicting Protein Kinase Specificity: Predikin Update and Performance in the DREAM4 Challenge

Figure 6

Predictive performance of old- and new-style position weight matrices.

The predictive power, as assessed by the area under the ROC curve analysis, of the new-style matrices (black dashed) is virtually identical to that of the old-style (red solid). Demonstrating that Frobenius distance does not necessary provide an insight as to which weight matrix is the best for predictive purposes.

Figure 6