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Predicting Protein Kinase Specificity: Predikin Update and Performance in the DREAM4 Challenge

Figure 1

Number of position weight matrices built using each BLOSUM matrix.

Each bar represents the number of kinases for which a position weight matrix could be built using each of 16 BLOSUM matrices. The blue bars show the number of position weight matrices built when using a cut-off value of 1, and the red bars show the number when using a cut-off value of 0. When considering just the number of position weight matrices, BLOSUM30 is clearly superior, and this is even more apparent when using a cut-off value of 0.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0021169.g001