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Impact of Cellular miRNAs on Circulating miRNA Biomarker Signatures

Figure 1

Fractionation Workflow.

Separation of whole blood into distinct fractions: WBC, RBC, Leukocytes and CS, S1, S2, P1, P2 through differential centrifugation. Total RNA was extracted from each fraction and hybridized to miRNA arrays.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0020769.g001