Comparative Genomics Suggests that the Fungal Pathogen Pneumocystis Is an Obligate Parasite Scavenging Amino Acids from Its Host's Lungs
Estimation of the quality of the mapping onto KEGG maps by performing a re-prediction of the annotation of S. pombe proteome through intermediary data set consisting of one, two, three, or 18 fungal proteomes.
The KO - S. pombe association pairs obtained by “blasting” an intermediary data set were evaluated a posteriori as true positive (TP) or false positive (FP) according to the KO - S. pombe mapping which is provided by KEGG. Those missed KO - S. pombe pairs existing in KEGG were taken as false negatives (FN). The overall quality of the obtained mapping can be expressed in terms of precision TP/(TP+FP) and recall TP/(TP+FN).