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Natural Killer Cell Tolerance Persists Despite Significant Reduction of Self MHC Class I on Normal Target Cells in Mice

Figure 1

MHC class I expression in mice hemizygous or homozygous for MHC class I.

Expression levels of MHC class I molecules in KbDb mice (upper two panels), Kb-single mice and Dd-single mice (lower two panels), as measured by flow cytometry. Thick black, thin grey and intermediate grey lines represent expression in hemizygous, homozygous and MHC class I-deficient mice, respectively. Figures show one representative mouse out of 14 stained for each mouse strain.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0013174.g001