Depo-Provera® Treatment Does Not Abrogate Protection from Intravenous SIV Challenge in Female Macaques Immunized with an Attenuated AIDS Virus
Figure 1
Plasma vRNA levels after IV challenge with SIVmac239.
(A) unimmunized macaques, (B) SHIV-immunized macaques and (C) progesterone-treated, SHIV-immunized macaques. In panel (D), cumulative vRNA levels over the 20 weeks of observation were transformed into areas under the curve (AUC) and the median AUC of the 3 groups of animals were compared. The Kruskal-Wallis test and a pair-wise comparison between the 2 groups of immunized animals and the unimmunized group using Dunn's multiple comparisons test were performed.