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The Anopheles gambiae Odorant Binding Protein 1 (AgamOBP1) Mediates Indole Recognition in the Antennae of Female Mosquitoes

Figure 2

In silico ligand binding studies on Anopheles gambiae OBP1.

(A) AgamOBP1 with indole fitted in the binding cavity. Cyan is the indole ring. Residues in red line the binding site. (B) Surface representation of the AgamOBP1 binding cavity (wired mesh) and indole (semi transparent continuous surface) showing the calculated binding position of indole fitted in the upper part of the binding site. (C) Predicted oleic acid (cyan) binding position indicating the L shaped binding cavity. Diagrams created with PYMOL (DeLano Scientific LLC).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0009471.g002