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Human Ovarian Reserve from Conception to the Menopause

Figure 7

Rates of NGF recruitment towards maturation.

Each sub-figure describes the absolute number of NGFs recruited per month, for ages from birth to 55 years, based on population decline predicted by the ADC model. Figure 7 (a) - red curve - denotes recruitment for individuals whose decline is in line with the average age at menopause; maximum recruitment of 880 follicles per month occurs at 14 years 2 months. Figure 7 (b) - green curve - denotes recruitment for individuals whose decline is in line with early age at menopause (the lower 95% prediction limit of the model); maximum recruitment of 104 follicles per month occurs at 14 years 2 months. Figure 7 (c) - yellow curve - denote recruitment in line with late age at menopause (the upper 95% prediction limit of the model); maximum recruitment of 7,520 follicles per month occurs at 14 years 2 months.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0008772.g007