Human Ovarian Reserve from Conception to the Menopause
The best model for the establishment of the NGF population after conception, and the subsequent decline until age at menopause is described by an ADC model with parameters = 5.56 (95% CI 5.38–5.74), = 25.6 (95% CI 24.9–26.4), = 52.7 (95% CI 51.1–54.2), = 0.074 (95% CI 0.062–0.085), and = 24.5 (95% CI 20.4–28.6). Our model has correlation coefficient = 0.81, fit standard error = 0.46 and F-value = 364. The figure shows the dataset (n = 325), the model, the 95% prediction limits of the model, and the 95% confidence interval for the model. The horizontal axis denotes age in months up to birth at age zero, and age in years from birth to 51 years.