Multiple Sclerosis: MicroRNA Expression Profiles Accurately Differentiate Patients with Relapsing-Remitting Disease from Healthy Controls
Figure 1
Histogram plot of the logarithm of fold changes, raw t-test p-values and adjusted p-values for all screened miRNAs.
The upper part of the figure shows the logarithms of fold changes. These are almost normally distributed between -3 and 3. The middle and bottom part of the figure present histograms of adjusted p-values for the limma test and t-test. The t-test showed a slightly decreased number of significant miRNAs. Nevertheless, for both tests a clear tendency towards low p-values and thus high significance can be seen. The vertical blue line denotes the significance threshold of 0.05.