Comparative Analysis of Viral Gene Expression Programs during Poxvirus Infection: A Transcriptional Map of the Vaccinia and Monkeypox Genomes
Figure 2
Early viral gene expression during poxvirus infection.
A subset of the complete monkeypox and vaccinia transcriptome representative of the early transcripts. Timecourses are as follows: Mock = mock infection (media only), VACV-WR = Vaccinia-Western Reserve, MPXV = Monkeypox-Zaire. Open Reading Frame (ORF), virus species, predicted timing of expression from VACV (Expr Time) [8] and protein function are displayed. Poxvirus ORFs were spotted in duplicate on arrays, and resulting gene expression values relative to baseline (time 0) are displayed. The intensity of the color reflects the magnitude of the change from baseline (−64 fold to 64 fold change from baseline).