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Stylus: A System for Evolutionary Experimentation Based on a Protein/Proteome Model with Non-Arbitrary Functional Constraints

Figure 12

Qualitative correlation between functional proficiency of vector proteins and their legibility.

Initial genes encoding (U+4EAB), (U+5F35), and (U+684C) were generated with Inscribe and processed with Stylus (see Software). Initial proficiencies were above 0.6. Selection thresholds ran from 0.60 to 0.10 in steps of −0.05, followed by thresholds of 0.07, 0.05, 0.03, and 0.01. At each threshold, 1000 non-synonymous base substitutions were accumulated. Vector proteins shown are representative of the distortion seen at the indicated scores.

Figure 12

doi: https://doi.org/10.1371/journal.pone.0002246.g012