Stylus: A System for Evolutionary Experimentation Based on a Protein/Proteome Model with Non-Arbitrary Functional Constraints
A) Two proteins that use similar NAD-binding domains (orange). Left: α-glucosidase monomer from Thermotoga maritima (PDB 1OBB). Right: L-lactate dehydrogenase monomer from Bacillus stearothermophilus (PDB 1LDN). B) Two vector proteins that use similar domains (purple) as described in text.