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Stylus: A System for Evolutionary Experimentation Based on a Protein/Proteome Model with Non-Arbitrary Functional Constraints

Figure 7

Domains as sub-structures with sub-functions.

A) Two proteins that use similar NAD-binding domains (orange). Left: α-glucosidase monomer from Thermotoga maritima (PDB 1OBB). Right: L-lactate dehydrogenase monomer from Bacillus stearothermophilus (PDB 1LDN). B) Two vector proteins that use similar domains (purple) as described in text.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0002246.g007