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Improving Phrap-Based Assembly of the Rat Using “Reliable” Overlaps

Figure 1

Illustration of the technique that identifies reliable overlaps: (a) a scenario where a genome contains two copies of a repeat region R.

The correct positions of reads A, B, C and D are shown. (b) A “fork” in the overlaps. (c) a scenario where reads A and D have the same sequencing error at the same base.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0001836.g001