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Open Access
Peer-reviewed
Research Article
Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers
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Xiaolong Wang ,
Contributed equally to this work with: Xiaolong Wang, Bei Cai, Jiankui Zhou
Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China
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Bei Cai ,
Contributed equally to this work with: Xiaolong Wang, Bei Cai, Jiankui Zhou
Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China
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Jiankui Zhou ,
Contributed equally to this work with: Xiaolong Wang, Bei Cai, Jiankui Zhou
Affiliations MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center of Nanjing University, National Resource Center for Mutant Mice, Nanjing 210061, China, School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China
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Haijing Zhu,
Affiliations Shaanxi Provincial Engineering and Technology Research Center of Cashmere Goats, Yulin 719000, China, Life Science Research Center, Yulin University, Yulin 719000, China
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Yiyuan Niu,
Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China
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Baohua Ma,
Affiliation College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China
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Honghao Yu,
Affiliations Shaanxi Provincial Engineering and Technology Research Center of Cashmere Goats, Yulin 719000, China, Life Science Research Center, Yulin University, Yulin 719000, China
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Anmin Lei,
Affiliation College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China
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Hailong Yan,
Affiliations College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China, Shaanxi Provincial Engineering and Technology Research Center of Cashmere Goats, Yulin 719000, China, Life Science Research Center, Yulin University, Yulin 719000, China
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Qiaoyan Shen,
Affiliation College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China
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Lei Shi,
Affiliations Shaanxi Provincial Engineering and Technology Research Center of Cashmere Goats, Yulin 719000, China, Life Science Research Center, Yulin University, Yulin 719000, China
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Xiaoe Zhao,
Affiliation College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China
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Jinlian Hua,
Affiliation College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China
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Xingxu Huang ,
* E-mail: chenyulin@nwafu.edu.cn (YC); ylqulei@126.com (LQ); xingxuhuang@mail.nju.edu.cn (XH)
Affiliations MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center of Nanjing University, National Resource Center for Mutant Mice, Nanjing 210061, China, School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China
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Lei Qu ,
* E-mail: chenyulin@nwafu.edu.cn (YC); ylqulei@126.com (LQ); xingxuhuang@mail.nju.edu.cn (XH)
Affiliations Shaanxi Provincial Engineering and Technology Research Center of Cashmere Goats, Yulin 719000, China, Life Science Research Center, Yulin University, Yulin 719000, China
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Yulin Chen
* E-mail: chenyulin@nwafu.edu.cn (YC); ylqulei@126.com (LQ); xingxuhuang@mail.nju.edu.cn (XH)
Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China
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Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers
- Xiaolong Wang,
- Bei Cai,
- Jiankui Zhou,
- Haijing Zhu,
- Yiyuan Niu,
- Baohua Ma,
- Honghao Yu,
- Anmin Lei,
- Hailong Yan,
- Qiaoyan Shen
- Published: October 18, 2016
- https://doi.org/10.1371/journal.pone.0164640