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Open Access
Peer-reviewed
Research Article
A Novel Immunodominant CD8+ T Cell Response Restricted by a Common HLA-C Allele Targets a Conserved Region of Gag HIV-1 Clade CRF01_AE Infected Thais
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Supranee Buranapraditkun ,
Contributed equally to this work with: Supranee Buranapraditkun, Ursula Hempel
Affiliations Vaccine and Cellular Immunology Laboratory, Chulalongkorn Medical Research Center (ChulaMRC), and Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, Interdisciplinary Program of Medical Microbiology, Graduate School, Chulalongkorn University, Bangkok, Thailand
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Ursula Hempel ,
Contributed equally to this work with: Supranee Buranapraditkun, Ursula Hempel
Affiliation Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America
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Patrawadee Pitakpolrat,
Affiliation Vaccine and Cellular Immunology Laboratory, Chulalongkorn Medical Research Center (ChulaMRC), and Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
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Rachel L. Allgaier,
Affiliation Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America
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Pattarawat Thantivorasit,
Affiliation Vaccine and Cellular Immunology Laboratory, Chulalongkorn Medical Research Center (ChulaMRC), and Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
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Sven-Iver Lorenzen,
Affiliation Vaccine and Cellular Immunology Laboratory, Chulalongkorn Medical Research Center (ChulaMRC), and Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
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Sunee Sirivichayakul,
Affiliation Vaccine and Cellular Immunology Laboratory, Chulalongkorn Medical Research Center (ChulaMRC), and Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
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William H. Hildebrand,
Affiliation Department of Microbiology and Immunology, Health Sciences Center, University of Oklahoma, Oklahoma City, Oklahoma, United States of America
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Marcus Altfeld,
Affiliation Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America
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Christian Brander,
Affiliation AIDS Research Institute IrsiCaixa - HIVACAT, Hospital Germans Trias i Pujol, Badalona, and Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain
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Bruce D. Walker,
Affiliation Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America
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Praphan Phanuphak,
Affiliations Vaccine and Cellular Immunology Laboratory, Chulalongkorn Medical Research Center (ChulaMRC), and Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, Thai Red Cross AIDS Research Center, Bangkok, Thailand
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Pokrath Hansasuta,
Affiliation Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
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Sarah L. Rowland-Jones,
Affiliation Medical Research Council, Human Immunology Unit, Weather all Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom
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Todd M. Allen ,
¶These authors also contributed equally to this work.
Affiliation Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America
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Kiat Ruxrungtham
* E-mail: kiat.r@chula.ac.th
¶These authors also contributed equally to this work.
Affiliations Vaccine and Cellular Immunology Laboratory, Chulalongkorn Medical Research Center (ChulaMRC), and Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, Thai Red Cross AIDS Research Center, Bangkok, Thailand
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A Novel Immunodominant CD8+ T Cell Response Restricted by a Common HLA-C Allele Targets a Conserved Region of Gag HIV-1 Clade CRF01_AE Infected Thais
- Supranee Buranapraditkun,
- Ursula Hempel,
- Patrawadee Pitakpolrat,
- Rachel L. Allgaier,
- Pattarawat Thantivorasit,
- Sven-Iver Lorenzen,
- Sunee Sirivichayakul,
- William H. Hildebrand,
- Marcus Altfeld,
- Christian Brander
- Published: August 22, 2011
- https://doi.org/10.1371/journal.pone.0023603