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Open Access
Peer-reviewed
Research Article
Genomic and Clinical Effects Associated with a Relaxation Response Mind-Body Intervention in Patients with Irritable Bowel Syndrome and Inflammatory Bowel Disease
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Braden Kuo ,
Contributed equally to this work with: Braden Kuo, Manoj Bhasin
¶‡ BK and MB are first authors on this work. TAL, JK, and JWD also contributed equally to this work and are senior authors on this work.
Affiliation Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Manoj Bhasin ,
Contributed equally to this work with: Braden Kuo, Manoj Bhasin
¶‡ BK and MB are first authors on this work. TAL, JK, and JWD also contributed equally to this work and are senior authors on this work.
Affiliations Division of Interdisciplinary Medicine & Biotechnology, and Genomics, Proteomics, Bioinformatics and Systems Biology Center, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Jolene Jacquart,
Affiliation Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Matthew A. Scult,
Affiliation Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Lauren Slipp,
Affiliation Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Eric Isaac Kagan Riklin,
Affiliation Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Veronique Lepoutre,
Affiliation Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Nicole Comosa,
Affiliation Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Beth-Ann Norton,
Affiliation Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Allison Dassatti,
Affiliation Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Jessica Rosenblum,
Affiliation Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Andrea H. Thurler,
Affiliation Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Brian C. Surjanhata,
Affiliation Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Nicole N. Hasheminejad,
Affiliation Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Leslee Kagan,
Affiliation Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Ellen Slawsby,
Affiliation Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Sowmya R. Rao,
Affiliations Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Center for Healthcare Organization and Implementation Research (CHOIR), Bedford VA Medical Center, Bedford, Massachusetts, United States of America
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Eric A. Macklin,
Affiliation MGH Biostatistics Center, Massachusetts General Hospital, Boston, MA, and Harvard Medical School, Boston, Massachusetts, United States of America
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Gregory L. Fricchione,
Affiliations Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Herbert Benson,
Affiliations Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Towia A. Libermann ,
¶‡ BK and MB are first authors on this work. TAL, JK, and JWD also contributed equally to this work and are senior authors on this work.
Affiliations Division of Interdisciplinary Medicine & Biotechnology, and Genomics, Proteomics, Bioinformatics and Systems Biology Center, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Joshua Korzenik ,
¶‡ BK and MB are first authors on this work. TAL, JK, and JWD also contributed equally to this work and are senior authors on this work.
Affiliations Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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John W. Denninger
* E-mail: jdenninger@mgh.harvard.edu
¶‡ BK and MB are first authors on this work. TAL, JK, and JWD also contributed equally to this work and are senior authors on this work.
Affiliations Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Genomic and Clinical Effects Associated with a Relaxation Response Mind-Body Intervention in Patients with Irritable Bowel Syndrome and Inflammatory Bowel Disease
- Braden Kuo,
- Manoj Bhasin,
- Jolene Jacquart,
- Matthew A. Scult,
- Lauren Slipp,
- Eric Isaac Kagan Riklin,
- Veronique Lepoutre,
- Nicole Comosa,
- Beth-Ann Norton,
- Allison Dassatti
- Published: April 30, 2015
- https://doi.org/10.1371/journal.pone.0123861