Evidence That Multiple Defects in Lipid Regulation Occur before Hyperglycemia during the Prodrome of Type-2 Diabetes

Simon G. Anderson; Warwick B. Dunn; Moulinath Banerjee; Marie Brown; David I. Broadhurst; Royston Goodacre; Garth J. S. Cooper; Douglas B. Kell; J. Kennedy Cruickshank

doi:10.1371/journal.pone.0103217

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Open Access

Peer-reviewed

Research Article

Evidence That Multiple Defects in Lipid Regulation Occur before Hyperglycemia during the Prodrome of Type-2 Diabetes

Simon G. Anderson ,

Contributed equally to this work with: Simon G. Anderson, Warwick B. Dunn

Affiliation Institute of Cardiovascular Sciences, Core Technology Facility, The University of Manchester, Manchester, United Kingdom
⨯
Warwick B. Dunn ,

Contributed equally to this work with: Simon G. Anderson, Warwick B. Dunn

Affiliations Manchester Centre for Integrative Systems Biology, Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom, Centre for Advanced Discovery & Experimental Therapeutics (CADET), Central Manchester NHS Foundation Trust and School of Biomedicine, The University of Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom
⨯
Moulinath Banerjee,

Affiliation Institute of Cardiovascular Sciences, Core Technology Facility, The University of Manchester, Manchester, United Kingdom
⨯
Marie Brown,

Affiliation Manchester Centre for Integrative Systems Biology, Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom
⨯
David I. Broadhurst,

Affiliations Manchester Centre for Integrative Systems Biology, Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom, Division of General Internal Medicine, Department of Medicine, 4126A Katz Group Centre for Pharmacy & Health, University of Alberta, Edmonton, Alberta, Canada
⨯
Royston Goodacre,

Affiliation Manchester Centre for Integrative Systems Biology, Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom
⨯
Garth J. S. Cooper,

Affiliations Centre for Advanced Discovery & Experimental Therapeutics (CADET), Central Manchester NHS Foundation Trust and School of Biomedicine, The University of Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom, Maurice Wilkins Centre for Molecular Biodiscovery, Faculty of Science, University of Auckland, Auckland, New Zealand, Department of Pharmacology, University of Oxford, Oxford, United Kingdom
⨯
Douglas B. Kell,

Affiliation Manchester Centre for Integrative Systems Biology, Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom
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J. Kennedy Cruickshank

* E-mail: kennedy.cruickshank@kcl.ac.uk

Affiliations Institute of Cardiovascular Sciences, Core Technology Facility, The University of Manchester, Manchester, United Kingdom, Diabetes & Nutritional Sciences Division, King's College London, London, United Kingdom
⨯

Evidence That Multiple Defects in Lipid Regulation Occur before Hyperglycemia during the Prodrome of Type-2 Diabetes

Simon G. Anderson,
Warwick B. Dunn,
Moulinath Banerjee,
Marie Brown,
David I. Broadhurst,
Royston Goodacre,
Garth J. S. Cooper,
Douglas B. Kell,
J. Kennedy Cruickshank

Published: September 3, 2014
https://doi.org/10.1371/journal.pone.0103217

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08 Oct 2014
19:58 GMT
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Multiple testing Posted by Hellgren on 08 Oct 2014 at 19:58 GMT

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