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Cortisol vs DHEA in Cancer and Depression: 1985 and 1997

Posted by jamesmhoward on 18 Sep 2012 at 13:05 GMT

The connection of stress, cortisol, with depression and cancer may have been explained as early as 1985 and 1994 / 7.

It is my hypothesis that low dehydroepiandrosterone (DHEA) is the major cause of breast cancer and other cancers (Annals of Internal Medicine 2005; 142: 471-472). This includes my explanation of low DHEA and cancer of 1994.

In 1985 I first suggested that low DHEA may produce depression; as far as I can determine, the first reports of low DHEA and depression appeared around 1989. (“A Theory of the Control of the Ontogeny and Phylogeny of Homo sapiens by the Interaction of Dehydroepiandrosterone and the Amygdala,” Copyright 1985, James Michael Howard, Fayetteville, Arkansas, U.S.A. (Registered Copyright Txu220580).

I wrote my detailed explanation of stress, cortisol, and DHEA in cancer in 1997: “Explanation of New Report of a Connection in Breast Cancer, Stress, and the Immune System,” at: .

The foregoing explains the findings of Cohen, et al. I suggest Cohen, et al., provides support for my work.

No competing interests declared.