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Open Access
Peer-reviewed
Research Article
Exome Capture Sequencing of Adenoma Reveals Genetic Alterations in Multiple Cellular Pathways at the Early Stage of Colorectal Tumorigenesis
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Donger Zhou ,
Contributed equally to this work with: Donger Zhou, Liu Yang
Affiliations The Key Laboratory of Cancer Prevention and Intervention of China National Ministry of Education, the Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province, Cancer Institute, Hangzhou, Zhejiang, China, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
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Liu Yang ,
Contributed equally to this work with: Donger Zhou, Liu Yang
Affiliations The Key Laboratory of Cancer Prevention and Intervention of China National Ministry of Education, the Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province, Cancer Institute, Hangzhou, Zhejiang, China, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
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Liangtao Zheng,
Affiliations The Key Laboratory of Cancer Prevention and Intervention of China National Ministry of Education, the Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province, Cancer Institute, Hangzhou, Zhejiang, China, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
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Weiting Ge,
Affiliations The Key Laboratory of Cancer Prevention and Intervention of China National Ministry of Education, the Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province, Cancer Institute, Hangzhou, Zhejiang, China, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
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Dan Li,
Affiliations The Key Laboratory of Cancer Prevention and Intervention of China National Ministry of Education, the Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province, Cancer Institute, Hangzhou, Zhejiang, China, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
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Yong Zhang,
Affiliation Beijing Genomics Institute (BGI)-Shenzhen, Shenzhen, China
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Xueda Hu,
Affiliation Beijing Genomics Institute (BGI)-Shenzhen, Shenzhen, China
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Zhibo Gao,
Affiliation Beijing Genomics Institute (BGI)-Shenzhen, Shenzhen, China
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Jinghong Xu,
Affiliation The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
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Yanqin Huang,
Affiliations The Key Laboratory of Cancer Prevention and Intervention of China National Ministry of Education, the Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province, Cancer Institute, Hangzhou, Zhejiang, China, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
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Hanguang Hu,
Affiliations The Key Laboratory of Cancer Prevention and Intervention of China National Ministry of Education, the Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province, Cancer Institute, Hangzhou, Zhejiang, China, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
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Hang Zhang,
Affiliations The Key Laboratory of Cancer Prevention and Intervention of China National Ministry of Education, the Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province, Cancer Institute, Hangzhou, Zhejiang, China, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
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Hao Zhang,
Affiliation Beijing Genomics Institute (BGI)-Shenzhen, Shenzhen, China
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Mingming Liu,
Affiliation Beijing Genomics Institute (BGI)-Shenzhen, Shenzhen, China
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Huanming Yang,
Affiliation Beijing Genomics Institute (BGI)-Shenzhen, Shenzhen, China
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Lei Zheng,
Affiliations Department of Oncology and Department of Surgery, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
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Shu Zheng
* E-mail: lzheng6@jhmi.edu
Affiliations The Key Laboratory of Cancer Prevention and Intervention of China National Ministry of Education, the Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province, Cancer Institute, Hangzhou, Zhejiang, China, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
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Exome Capture Sequencing of Adenoma Reveals Genetic Alterations in Multiple Cellular Pathways at the Early Stage of Colorectal Tumorigenesis
- Donger Zhou,
- Liu Yang,
- Liangtao Zheng,
- Weiting Ge,
- Dan Li,
- Yong Zhang,
- Xueda Hu,
- Zhibo Gao,
- Jinghong Xu,
- Yanqin Huang
- Published: January 2, 2013
- https://doi.org/10.1371/journal.pone.0053310