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Functional assignment method

Posted by matram on 12 Feb 2012 at 09:51 GMT

I find this paper very useful and interesting, but I've got a curiosity that someone can maybe satisfy. The work is much confident on blast-based functional assignment. I was wondering what would have been the results with profile-based searches (e.g. RPS-Blast) that are known to tolerate much more the "evolution" of functional modules.


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