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Referee comments: Referee 2 (Gerry Wright)

Posted by PLOS_ONE_Group on 25 Feb 2008 at 12:11 GMT

Referee 2's review (Gerry Wright):

This is a valuable addition to the growing literature that indicates that antibiotic resistance, like antibiotic action, is multifactorial. The results are thought provoking and important as we consider how to develop the next generations of antibiotics.

N.B. These are the comments made by the referee when reviewing an earlier version of this paper. Prior to publication the manuscript has been revised in light of these comments and to address other editorial requirements.