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Referee comments: Referee 2

Posted by PLOS_ONE_Group on 03 Mar 2008 at 12:36 GMT

Referee 2's review:

1. Are the experiments, statistics, and other analyses performed to a sufficient technical standard?


2. Are the conclusions presented in an appropriate fashion with speculations and hypotheses identified as such?

YES. The paper is mainly validating a technique in a new system.

3. Have the techniques used been documented in sufficient detail to allow replication?


4. Is the report presented in an intelligible fashion and written in English?


5. Have the exact results reported been published elsewhere?

Not to my knowledge.

6. Does the research meet all applicable standards with regard to the ethics of human / animal experimentation, participants' consent, and research integrity?


7. Has the report adhered to the relevant community standards for research conduct, presentation of results, and deposition of data, where appropriate?


N.B. These are the comments made by the referee when reviewing an earlier version of this paper. Prior to publication the manuscript has been revised in light of these comments and to address other editorial requirements.