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Phenotype marker of Tregs

Posted by ekallas on 28 Jan 2007 at 03:07 GMT

CD4+CD25+CD127−
http://plosone.org/article/info:doi/10.1371/journal.pone.0000102#article1.front1.article-meta1.abstract1.sec2.p1

Liu W, Putnam AL, Xu-Yu Z, Szot GL, Lee MR, Zhu S, Gottlieb PA, Kapranov P, Gingeras TR, Fazekas de St Groth B, Clayberger C, Soper DM, Ziegler SF, Bluestone JA.
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells.
J Exp Med. 2006 Jul 10;203(7):1701-11