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undiagnosed depression

Posted by smanzanares on 04 Mar 2011 at 10:55 GMT

Congratulations for your work, first of all. The prevalence of undiagnosed depression is quite high, how did you deal with that in your study? Wouldn't it bias the results to some extent?
Thank you

No competing interests declared.

RE: undiagnosed depression

MAM-G replied to smanzanares on 13 Mar 2011 at 18:15 GMT

Thank you for your kind comment.

Undiagnosed depression equals to low sensitivity.

We have already addressed this concern in the discussion section of our published version when we stated that
"Our validation study found very high specificity (0.96) for the self-reported diagnosis of depression. Theoretically, with perfect specificity, even when non-differential misclassification of disease because of low sensitivity exists, this will not bias the relative risk estimate.
Please check our reference #65.

No competing interests declared.