Genetic variant in vitamin D-binding protein is associated with metabolic syndrome and lower 25-hydroxyvitamin D levels in polycystic ovary syndrome: A cross-sectional study

Betânia Rodrigues Santos; Sheila Bünecker Lecke; Poli Mara Spritzer

doi:10.1371/journal.pone.0173695

Loading metrics

Open Access

Peer-reviewed

Research Article

Genetic variant in vitamin D-binding protein is associated with metabolic syndrome and lower 25-hydroxyvitamin D levels in polycystic ovary syndrome: A cross-sectional study

Betânia Rodrigues Santos,

Affiliations Gynecological Endocrinology Unit, Division of Endocrinology, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, Laboratory of Molecular Endocrinology, Department of Physiology, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
⨯
Sheila Bünecker Lecke,

Affiliations Gynecological Endocrinology Unit, Division of Endocrinology, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, Department of Diagnostic Methods, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil
⨯
Poli Mara Spritzer

* E-mail: spritzer@ufrgs.br

Affiliations Gynecological Endocrinology Unit, Division of Endocrinology, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, Laboratory of Molecular Endocrinology, Department of Physiology, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
⨯

Genetic variant in vitamin D-binding protein is associated with metabolic syndrome and lower 25-hydroxyvitamin D levels in polycystic ovary syndrome: A cross-sectional study

Betânia Rodrigues Santos,
Sheila Bünecker Lecke,
Poli Mara Spritzer

Published: March 9, 2017
https://doi.org/10.1371/journal.pone.0173695

About the Authors

Betânia Rodrigues Santos

Affiliations Gynecological Endocrinology Unit, Division of Endocrinology, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, Laboratory of Molecular Endocrinology, Department of Physiology, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

Sheila Bünecker Lecke

Affiliations Gynecological Endocrinology Unit, Division of Endocrinology, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, Department of Diagnostic Methods, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

Poli Mara Spritzer

* E-mail: spritzer@ufrgs.br

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: BRS PMS. Data curation: BRS. Formal analysis: BRS PMS. Funding acquisition: PMS. Investigation: BRS SBL PMS. Methodology: BRS PMS. Project administration: PMS. Resources: PMS. Supervision: PMS. Validation: BRS SBL PMS. Visualization: BRS SBL. Writing – original draft: BRS PMS. Writing – review & editing: BRS SBL PMS.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Polycystic ovary syndrome
Is the Subject Area "Polycystic ovary syndrome" applicable to this article?

Thanks for your feedback.
Haplotypes
Is the Subject Area "Haplotypes" applicable to this article?

Thanks for your feedback.
Vitamin D
Is the Subject Area "Vitamin D" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Vitamin D deficiency
Is the Subject Area "Vitamin D deficiency" applicable to this article?

Thanks for your feedback.
Metabolic syndrome
Is the Subject Area "Metabolic syndrome" applicable to this article?

Thanks for your feedback.
Variant genotypes
Is the Subject Area "Variant genotypes" applicable to this article?

Thanks for your feedback.
Cholesterol
Is the Subject Area "Cholesterol" applicable to this article?

Thanks for your feedback.