About the Authors

Caroline Brandl

Affiliations Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany, Department of Ophthalmology, University Hospital Regensburg, Regensburg, Germany, Institute of Human Genetics, University of Regensburg, Regensburg, Germany

Valentin Breinlich

Affiliation Institute of Human Genetics, University of Regensburg, Regensburg, Germany

Klaus J. Stark

Affiliation Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany

Sabrina Enzinger

Affiliation Statistical Consulting Unit StaBLab, Department of Statistics, Ludwig-Maximilians-University Munich, Germany

Matthias Aßenmacher

Affiliation Statistical Consulting Unit StaBLab, Department of Statistics, Ludwig-Maximilians-University Munich, Germany

Matthias Olden

Affiliation Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany

Felix Grassmann

Affiliation Institute of Human Genetics, University of Regensburg, Regensburg, Germany

Jochen Graw

Affiliation Institute of Developmental Genetics, Helmholtz-Zentrum München, Neuherberg, Germany

Margit Heier

Affiliation Institute for Epidemiology II, Helmholtz-Zentrum München, Neuherberg, Germany

Annette Peters

Affiliation Institute for Epidemiology II, Helmholtz-Zentrum München, Neuherberg, Germany

Horst Helbig

Affiliation Department of Ophthalmology, University Hospital Regensburg, Regensburg, Germany

Helmut Küchenhoff

Affiliation Statistical Consulting Unit StaBLab, Department of Statistics, Ludwig-Maximilians-University Munich, Germany

Bernhard H. F. Weber

‡ These authors supervised this work jointly.

Affiliation Institute of Human Genetics, University of Regensburg, Regensburg, Germany

Iris M. Heid

iris.heid@klinik.uni-regensburg.de

‡ These authors supervised this work jointly.

Affiliations Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany, Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Competing Interests

Author H.H. has received lecture honorarium, travel support and is a member of the advisory board of the companies Bayer AG (Leverkusen, Germany), Allergan (Dublin, Ireland), and Novartis Pharma GmbH (Nürnberg, Germany). All other authors have declared that no competing interests exist. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: CB BHFW IMH. Data curation: KJS. Formal analysis: VB KJS SE MA FG HK IMH. Funding acquisition: AP IMH. Investigation: CB VB MH JG. Methodology: CB AP HK IMH. Project administration: AP HK BHFW IMH. Resources: MH AP KJS MO IMH. Software: MO. Supervision: AP HH HK BHFW IMH. Visualization: CB VB SE MA IMH. Writing – original draft: CB KJS HH HK BHFW IMH. Writing – review & editing: CB KJS HH HK BHFW IMH.