About the Authors

Takumi Tochio

Contributed equally to this work with: Takumi Tochio, Yasuyuki Kitaura

Affiliation B Food Science Co., Ltd., Chita, Aichi, Japan

Yasuyuki Kitaura

Contributed equally to this work with: Takumi Tochio, Yasuyuki Kitaura

Affiliation Laboratory of Nutritional Biochemistry, Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Aichi, Japan

Saki Nakamura

Affiliation B Food Science Co., Ltd., Chita, Aichi, Japan

Chie Sugawa

Affiliation B Food Science Co., Ltd., Chita, Aichi, Japan

Motoki Takahashi

Affiliation Laboratory of Nutritional Biochemistry, Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Aichi, Japan

Akihito Endo

Affiliation Department of Food and Cosmetic Science, Faculty of Bioindustry, Tokyo University of Agriculture, Abashiri, Hokkaido, Japan

Yoshiharu Shimomura

shimo@agr.nagoya-u.ac.jp

Affiliation Laboratory of Nutritional Biochemistry, Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Aichi, Japan

Competing Interests

The project was partially funded by the B Food Science Co., Ltd., to YS. TT, SN, and CS are employed by the Food Science Co., Ltd. There are no declarations relating to consultancy, patents or products in development or marketed products with regard to this work. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceptualization: TT YS. Data curation: YK TT AE YS. Formal analysis: YK. Funding acquisition: YS. Investigation: YK SN CS AE MT. Methodology: YS YK. Project administration: YS. Resources: TT. Software: YK. Supervision: YS. Validation: YS YK. Visualization: YS. Writing – original draft: TT. Writing – review & editing: YS.