About the Authors

Sebastian Brachs

Affiliations Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité –University School of Medicine, Berlin, Germany, German Center for Cardiovascular Research, DZHK Partner site Berlin, Berlin, Germany

Angelika F. Winkel

Affiliation Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, Germany

James Polack

Affiliations Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité –University School of Medicine, Berlin, Germany, German Center for Cardiovascular Research, DZHK Partner site Berlin, Berlin, Germany

Hui Tang

Affiliations Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité –University School of Medicine, Berlin, Germany, German Center for Cardiovascular Research, DZHK Partner site Berlin, Berlin, Germany

Maria Brachs

Affiliations Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité –University School of Medicine, Berlin, Germany, German Center for Cardiovascular Research, DZHK Partner site Berlin, Berlin, Germany

Daniel Margerie

Affiliation Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, Germany

Bodo Brunner

Affiliation Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, Germany

Kerstin Jahn-Hofmann

Affiliation Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, Germany

Hartmut Ruetten

Affiliation Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, Germany

Joachim Spranger

joachim.spranger@charite.de

Affiliations Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité –University School of Medicine, Berlin, Germany, German Center for Cardiovascular Research, DZHK Partner site Berlin, Berlin, Germany

Dieter Schmoll

Affiliation Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, Germany

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: This work was supported by Sanofi-Aventis Deutschland GmbH. AFW, DM, BB, KJ-H, HR, and DS are employees of Sanofi. All other authors disclose any duality of interest associated with their contribution to this manuscript. There are no patents, products in development or marketed products to declare. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: JS DS. Data curation: SB DM DS. Formal analysis: SB DM DS. Funding acquisition: HR DS JS. Investigation: SB AFW JP HT DM BB KJH DS. Methodology: SB BB KJH JS DS. Project administration: SB DS. Resources: SB AFW DM BB KJH DS. Supervision: JS. Validation: SB DM JS DS. Visualization: SB. Writing – original draft: SB DS. Writing – review & editing: SB JP MB JS DS.