About the Authors

Yukio Sato

Contributed equally to this work with: Yukio Sato, Yo Mabuchi

Affiliations Department of Emergency and Critical Care Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan, Department of Physiology, Keio University School of Medicine, Tokyo 160-8582, Japan, Institute of Medical Science, Tokyo Medical University, Tokyo 160-0023, Japan

Yo Mabuchi

Contributed equally to this work with: Yukio Sato, Yo Mabuchi

Affiliations Department of Physiology, Keio University School of Medicine, Tokyo 160-8582, Japan, Tokyo Medical and Dental University, Graduate School of Health Care Sciences, Department of Biochemistry and Biophysics, Tokyo 113-8510, Japan

Kenichi Miyamoto

Affiliation Shimane University Faculty of Medicine, Department of Life Science, Shimane 693-8501, Japan

Daisuke Araki

Affiliation Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan

Kunimichi Niibe

Affiliations Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan, Division of Molecular and Regenerative Prosthodontics, Tohoku University Graduate School of Dentistry, Miyagi 980-8575, Japan

Diarmaid D. Houlihan

Affiliation Centre for Liver Research, NIHR Biomedical Research Unit, University of Birmingham, Birmingham B15 2TT, United Kingdom

Satoru Morikawa

Affiliation Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan

Taneaki Nakagawa

Affiliation Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan

Toshihiro Nakajima

Affiliation Institute of Medical Science, Tokyo Medical University, Tokyo 160-0023, Japan

Chihiro Akazawa

Affiliation Tokyo Medical and Dental University, Graduate School of Health Care Sciences, Department of Biochemistry and Biophysics, Tokyo 113-8510, Japan

Shingo Hori

Affiliation Department of Emergency and Critical Care Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan

Hideyuki Okano

Affiliation Department of Physiology, Keio University School of Medicine, Tokyo 160-8582, Japan

Yumi Matsuzaki

matsuzak@med.shimane-u.ac.jp

Affiliations Department of Physiology, Keio University School of Medicine, Tokyo 160-8582, Japan, Institute of Medical Science, Tokyo Medical University, Tokyo 160-0023, Japan, Shimane University Faculty of Medicine, Department of Life Science, Shimane 693-8501, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: YS DA HO Y. Matsuzaki. Formal analysis: YS Y. Mabuchi KM DA KN. Investigation: KM KN DDH SM. Methodology: YS Y. Mabuchi SM. Resources: T. Nakagawa T. Nakajima CA SH HO. Supervision: Y. Matsuzaki. Writing – original draft: YS Y. Mabuchi DDH Y. Matsuzaki. Writing – review & editing: YS Y. Mabuchi Y. Matsuzaki.