Computational prediction of the tolerance to amino-acid deletion in green-fluorescent protein

Eleisha L. Jackson; Stephanie J. Spielman; Claus O. Wilke

doi:10.1371/journal.pone.0164905

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Open Access

Peer-reviewed

Research Article

Computational prediction of the tolerance to amino-acid deletion in green-fluorescent protein

Eleisha L. Jackson,

Affiliations Department of Integrative Biology, The University of Texas at Austin, Austin, Texas, United States of America, Center for Computational Biology and Bioinformatics, The University of Texas at Austin, Austin, Texas, United States of America, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas, United States of America
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Stephanie J. Spielman,

Affiliation Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, Pennsylvania, United States of America
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Claus O. Wilke

* E-mail: wilke@austin.utexas.edu

Affiliations Department of Integrative Biology, The University of Texas at Austin, Austin, Texas, United States of America, Center for Computational Biology and Bioinformatics, The University of Texas at Austin, Austin, Texas, United States of America, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas, United States of America

http://orcid.org/0000-0002-7470-9261

⨯

Computational prediction of the tolerance to amino-acid deletion in green-fluorescent protein

Eleisha L. Jackson,
Stephanie J. Spielman,
Claus O. Wilke

Published: April 3, 2017
https://doi.org/10.1371/journal.pone.0164905
See the preprint

About the Authors

Eleisha L. Jackson

Affiliations Department of Integrative Biology, The University of Texas at Austin, Austin, Texas, United States of America, Center for Computational Biology and Bioinformatics, The University of Texas at Austin, Austin, Texas, United States of America, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas, United States of America

Stephanie J. Spielman

Affiliation Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, Pennsylvania, United States of America

Claus O. Wilke

* E-mail: wilke@austin.utexas.edu

http://orcid.org/0000-0002-7470-9261

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: ELJ SJS COW. Formal analysis: ELJ. Funding acquisition: ELJ SJS COW. Investigation: ELJ. Methodology: ELJ COW. Software: ELJ. Supervision: COW. Visualization: ELJ COW. Writing – original draft: ELJ. Writing – review & editing: ELJ SJS COW.

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Protein structure prediction
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Protein structure
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Macromolecular design
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Support vector machines
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Deletion mutagenesis
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Chromophores
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Molecular evolution
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Deletion mutation
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