Evolution of the Twist Subfamily Vertebrate Proteins: Discovery of a Signature Motif and Origin of the Twist1 Glycine-Rich Motifs in the Amino-Terminus Disordered Domain

Yacidzohara Rodriguez; Ricardo R. Gonzalez-Mendez; Carmen L. Cadilla

doi:10.1371/journal.pone.0161029

Loading metrics

Open Access

Peer-reviewed

Research Article

Evolution of the Twist Subfamily Vertebrate Proteins: Discovery of a Signature Motif and Origin of the Twist1 Glycine-Rich Motifs in the Amino-Terminus Disordered Domain

Yacidzohara Rodriguez,

Affiliation Department of Biochemistry, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico, United States of America
⨯
Ricardo R. Gonzalez-Mendez,

Affiliation Department of Radiological Sciences, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico, United States of America
⨯
Carmen L. Cadilla

* E-mail: carmen.cadilla@upr.edu

Affiliation Department of Biochemistry, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico, United States of America

http://orcid.org/0000-0002-6676-1086

⨯

Evolution of the Twist Subfamily Vertebrate Proteins: Discovery of a Signature Motif and Origin of the Twist1 Glycine-Rich Motifs in the Amino-Terminus Disordered Domain

Yacidzohara Rodriguez,
Ricardo R. Gonzalez-Mendez,
Carmen L. Cadilla

Published: August 24, 2016
https://doi.org/10.1371/journal.pone.0161029

About the Authors

Yacidzohara Rodriguez

Affiliation Department of Biochemistry, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico, United States of America

Ricardo R. Gonzalez-Mendez

Affiliation Department of Radiological Sciences, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico, United States of America

Carmen L. Cadilla

* E-mail: carmen.cadilla@upr.edu

Affiliation Department of Biochemistry, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico, United States of America

http://orcid.org/0000-0002-6676-1086

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YR RGM CLC. Performed the experiments: YR RGM. Analyzed the data: YR RGM CLC. Contributed reagents/materials/analysis tools: RGM. Wrote the paper: YR RGM CLC.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mammals
Is the Subject Area "Mammals" applicable to this article?

Thanks for your feedback.
Sequence motif analysis
Is the Subject Area "Sequence motif analysis" applicable to this article?

Thanks for your feedback.
Vertebrates
Is the Subject Area "Vertebrates" applicable to this article?

Thanks for your feedback.
Protein domains
Is the Subject Area "Protein domains" applicable to this article?

Thanks for your feedback.
Amphioxus
Is the Subject Area "Amphioxus" applicable to this article?

Thanks for your feedback.
Protein structure prediction
Is the Subject Area "Protein structure prediction" applicable to this article?

Thanks for your feedback.
Phylogenetic analysis
Is the Subject Area "Phylogenetic analysis" applicable to this article?

Thanks for your feedback.
Reptiles
Is the Subject Area "Reptiles" applicable to this article?

Thanks for your feedback.