About the Authors

Matthew H. Wong

matt.wong@health.nsw.gov.au

Affiliations Department of Medical Oncology, Gosford Hospital, Gosford, Australia, Kolling Institute of Medical Research, University of Sydney, Sydney, Australia

David L. Chan

Affiliations Kolling Institute of Medical Research, University of Sydney, Sydney, Australia, Department of Medical Oncology, Royal North Shore Hospital, Sydney, Australia

Adrian Lee

Affiliations Kolling Institute of Medical Research, University of Sydney, Sydney, Australia, Department of Medical Oncology, Royal North Shore Hospital, Sydney, Australia, Northern Cancer Institute, Sydney, Australia

Bob T. Li

Affiliations Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Sydney Medical School, University of Sydney, Sydney, Australia

Sumit Lumba

Affiliation Department of Medical Oncology, Royal North Shore Hospital, Sydney, Australia

Stephen J. Clarke

Affiliations Kolling Institute of Medical Research, University of Sydney, Sydney, Australia, Department of Medical Oncology, Royal North Shore Hospital, Sydney, Australia

Jaswinder Samra

Affiliation Department of Gastrointestinal Surgery, Royal North Shore and Macquarie University Hospitals, Sydney, Australia

Nick Pavlakis

Affiliations Kolling Institute of Medical Research, University of Sydney, Sydney, Australia, Department of Medical Oncology, Royal North Shore Hospital, Sydney, Australia

Competing Interests

DLC has received honoraria from Ipsen and travel support from Novartis. NP has received honoraria from Bayer, Roche and Sanofi; provided advice to Roche, Merck, Bayer, Sanofi and Amgen; and received a travel grant from Roche. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MHW AL BTL SL NP. Performed the experiments: MHW AL BTL DLC NP. Analyzed the data: MHW AL DLC BTL JS NP. Wrote the paper: MHW AL DLC BTL SL SJC JS NP.