Plasma Levels of the Interleukin-1-Receptor Antagonist Are Lower in Women with Gestational Diabetes Mellitus and Are Particularly Associated with Postpartum Development of Type 2 Diabetes

Pernilla Katra; Jonatan Dereke; Charlotta Nilsson; Magnus Hillman

doi:10.1371/journal.pone.0155701

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Open Access

Peer-reviewed

Research Article

Plasma Levels of the Interleukin-1-Receptor Antagonist Are Lower in Women with Gestational Diabetes Mellitus and Are Particularly Associated with Postpartum Development of Type 2 Diabetes

Pernilla Katra,

Affiliation Department of Clinical Sciences, Diabetes Research Laboratory, Lund University, Lund, Sweden
⨯
Jonatan Dereke,

Affiliation Department of Clinical Sciences, Diabetes Research Laboratory, Lund University, Lund, Sweden
⨯
Charlotta Nilsson,

Affiliations Department of Clinical Sciences, Diabetes Research Laboratory, Lund University, Lund, Sweden, Department of Pediatrics, Helsingborg Hospital, Helsingborg, Sweden
⨯
Magnus Hillman

* E-mail: magnus.hillman@med.lu.se

Affiliation Department of Clinical Sciences, Diabetes Research Laboratory, Lund University, Lund, Sweden

http://orcid.org/0000-0001-6749-2829

⨯

Plasma Levels of the Interleukin-1-Receptor Antagonist Are Lower in Women with Gestational Diabetes Mellitus and Are Particularly Associated with Postpartum Development of Type 2 Diabetes

Pernilla Katra,
Jonatan Dereke,
Charlotta Nilsson,
Magnus Hillman

Published: May 25, 2016
https://doi.org/10.1371/journal.pone.0155701

About the Authors

Pernilla Katra

Affiliation Department of Clinical Sciences, Diabetes Research Laboratory, Lund University, Lund, Sweden

Jonatan Dereke

Affiliation Department of Clinical Sciences, Diabetes Research Laboratory, Lund University, Lund, Sweden

Charlotta Nilsson

Affiliations Department of Clinical Sciences, Diabetes Research Laboratory, Lund University, Lund, Sweden, Department of Pediatrics, Helsingborg Hospital, Helsingborg, Sweden

Magnus Hillman

* E-mail: magnus.hillman@med.lu.se

Affiliation Department of Clinical Sciences, Diabetes Research Laboratory, Lund University, Lund, Sweden

http://orcid.org/0000-0001-6749-2829

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JD CN MH. Performed the experiments: PK JD. Analyzed the data: PK JD MH. Contributed reagents/materials/analysis tools: CN MH. Wrote the paper: PK JD MH. Ethical approval: CN MH. Critical appraisal of the manuscript: CN.

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Type 2 diabetes
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Diabetes mellitus
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Pregnancy
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Biomarkers
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Blood plasma
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Diagnostic medicine
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Hyperglycemia
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Insulin resistance
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