About the Authors

Hayley B. Clay

Affiliations Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, United States of America, Neuroscience Graduate Program, Vanderbilt University, Nashville, Tennessee, United States of America

Angelika K. Parl

Affiliation Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, United States of America

Sabrina L. Mitchell

Affiliation Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, United States of America

Larry Singh

Affiliation Center for Mitochondrial and Epigenomic Medicine, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Lauren N. Bell

Affiliation Metabolon, Incorporated, Durham, North Carolina, United States of America

Deborah G. Murdock

murdockd@email.chop.edu

Affiliation Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, United States of America

Competing Interests

The authors have the following interests: Dr. Lauren N. Bell is an employee of Metabolon, Inc. and, as such, has affiliations with or financial involvement with Metabolon, Inc. She has no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DGM HBC SLM AKP. Performed the experiments: DGM HBC SLM AKP LNB. Analyzed the data: DGM HBC SLM LNB LS. Contributed reagents/materials/analysis tools: DGM LNB. Wrote the paper: HBC DGM SLM AKP LNB.