About the Authors

Gaku Nakato

Current address: Dermatology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, United States of America

Affiliations Laboratory for Intestinal Ecosystem, RCAI, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Kanagawa, Japan, Laboratory for Immunobiology, Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan

Koji Hase

Current address: Division of Biochemistry, Faculty of Pharmacy, Keio University, Tokyo, Japan

Affiliations Laboratory for Intestinal Ecosystem, RCAI, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Kanagawa, Japan, Division of Mucosal Barriology, International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan, PRESTO, Japan Science and Technology Agency, Tokyo, Japan

Takao Sato

Affiliations Laboratory for Intestinal Ecosystem, RCAI, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Kanagawa, Japan, Laboratory for Immunobiology, Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan

Shunsuke Kimura

Affiliation Laboratory of Histology and Cytology, Graduate School of Medicine, Hokkaido University, Hokkaido, Japan

Sayuri Sakakibara

Affiliation Laboratory for Intestinal Ecosystem, RCAI, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Kanagawa, Japan

Machiko Sugiyama

Affiliation Laboratory for Immunobiology, Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan

Yuuki Obata

Affiliations Laboratory for Intestinal Ecosystem, RCAI, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Kanagawa, Japan, Division of Mucosal Barriology, International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan, Graduate School of Medical and Pharmaceutical Sciences, Chiba University, Chiba, Japan

Misaho Hanazato

Affiliations Laboratory for Intestinal Ecosystem, RCAI, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Kanagawa, Japan, Laboratory for Immunobiology, Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan

Toshihiko Iwanaga

Affiliation Laboratory of Histology and Cytology, Graduate School of Medicine, Hokkaido University, Hokkaido, Japan

Hiroshi Ohno

hiroshi.ohno@riken.jp

Affiliations Laboratory for Intestinal Ecosystem, RCAI, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Kanagawa, Japan, Laboratory for Immunobiology, Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GN KH HO. Performed the experiments: GN TS SK SS MS YO MH TI. Analyzed the data: GN TS SK SS MS YO MH TI. Wrote the paper: GN HO.