About the Authors

Paula Giselle Czaikoski

Contributed equally to this work with: Paula Giselle Czaikoski, José Maurício Segundo Correia Mota

Affiliation Department of Pharmacology, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

José Maurício Segundo Correia Mota

Contributed equally to this work with: Paula Giselle Czaikoski, José Maurício Segundo Correia Mota

Affiliation Department of Clinics, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

Daniele Carvalho Nascimento

Affiliation Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

Fabiane Sônego

Affiliation Department of Pharmacology, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

Fernanda Vargas e Silva Castanheira

Affiliation Department of Pharmacology, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

Paulo Henrique Melo

Affiliation Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

Gabriela Trentin Scortegagna

Affiliation Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

Rangel Leal Silva

Affiliation Department of Pharmacology, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

Romualdo Barroso-Sousa

Affiliation Department of Clinics, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

Fabrício Oliveira Souto

Affiliation Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

Antonio Pazin-Filho

Affiliation Department of Clinics, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

Florencio Figueiredo

Affiliation Department of Pathology, School of Medicine, University of Brasilia, Brasilia, Brazil

José Carlos Alves-Filho

Affiliation Department of Pharmacology, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

Fernando Queiróz Cunha

fdqcunha@fmrp.usp.br

Affiliation Department of Pharmacology, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil

Competing Interests

The authors declare that the co-author José Carlos Alves-Filho is part of the editorial board of PLOS ONE. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: PGC JMM APF FF JCAF FQC. Performed the experiments: PGC JMM DCN FS FVSC PHM GTS RLS RBS FOS. Analyzed the data: PGC JMM DCN FS FVSC PHM GTS RLS RBS FOS APF FF JCAF FQC. Contributed reagents/materials/analysis tools: FQC. Wrote the paper: PGC JMM FS FVSC RLS AP FF JCAF FQC. Analyzed histopathological slides: FF.