About the Authors
- Yasumasa Kimura
-
Contributed equally to this work with: Yasumasa Kimura, Takahiro Soma
* E-mail: y.kimura.sc@gmail.com (YK); matthias.harbers@riken.jp (MH)
Current Address: Division of Systems Immunology, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108–8639, Japan.
Affiliations K.K. DNAFORM, 75–1, Ono-cho, Tsurumi-ku, Yokohama, Kanagawa, 230–0046, Japan, RIKEN Center for Life Science Technologies, Division of Genomic Technologies, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230–0045, Japan
- Takahiro Soma
-
Contributed equally to this work with: Yasumasa Kimura, Takahiro Soma
Affiliation RIKEN Center for Life Science Technologies, Division of Genomic Technologies, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230–0045, Japan
- Naoko Kasahara
-
Current Address: Department of Bioclinical Informatics, Tohoku Medical Megabank Organization, Tohoku University, 2–1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980–8573, Japan.
Affiliation RIKEN Omics Science Center, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230–0045, Japan
- Diane Delobel
-
Affiliation RIKEN Center for Life Science Technologies, Division of Genomic Technologies, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230–0045, Japan
- Takeshi Hanami
-
Affiliation RIKEN Center for Life Science Technologies, Division of Genomic Technologies, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230–0045, Japan
- Yuki Tanaka
-
Affiliation RIKEN Center for Life Science Technologies, Division of Genomic Technologies, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230–0045, Japan
- Michiel J. L. de Hoon
-
Affiliation RIKEN Center for Life Science Technologies, Division of Genomic Technologies, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230–0045, Japan
- Yoshihide Hayashizaki
-
Affiliation RIKEN Preventive Medicine & Diagnosis Innovation Program, 2–1 Hirosawa, Wako-shi, Saitama, 351–0198, Japan
- Kengo Usui
-
Affiliations RIKEN Center for Life Science Technologies, Division of Genomic Technologies, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230–0045, Japan, RIKEN Preventive Medicine & Diagnosis Innovation Program, 2–1 Hirosawa, Wako-shi, Saitama, 351–0198, Japan
- Matthias Harbers
-
* E-mail: y.kimura.sc@gmail.com (YK); matthias.harbers@riken.jp (MH)
Affiliation RIKEN Center for Life Science Technologies, Division of Genomic Technologies, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230–0045, Japan
Competing Interests
YK and MH had been employees of K.K. DNAFORM, a company holding commercial rights to Eprimer and Eprobe technology. YK is an inventor of Japanese Patent Application 2012-158229 (”Nucleic acid probe, design method of nucleic acid probe, and detection method for target sequence”, WO 2014/013954 A1). TS and TH are inventors of Japanese Patent Application 2012-091400 (”New fluorescent material for labeling biomolecules”) and Japanese Patent Application 2012-158229 (”Nucleic acid probe, design method of nucleic acid probe, and detection method for target sequence”, WO 2014/013954 A1). YH is an inventor of Japanese Patent No. 4370385 (”Primer, primer set, and nucleic acid amplification method and mutation detection method using the same”, US8067162 B2, EP1970453 B1) and Japanese Patent Application 2012-091400 (”New fluorescent material for labeling biomolecules”) and Japanese Patent Application 2012-158229 (”Nucleic acid probe, design method of nucleic acid probe, and detection method for target sequence”, WO 2014/013954 A1). There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: YK TS TH YT YH KU MH. Performed the experiments: TS DD. Analyzed the data: YK TS DD TH MH. Contributed reagents/materials/analysis tools: YK. Wrote the paper: YK MH. Designed the software: YK NK MJLdH. Developed the software: YK NK.