About the Authors

Zafar Zafari

zafar.zafari@ubc.ca

Affiliations Institute for Heart and Lung Health (IHLH), Faculty of Medicine, University of British Columbia, Vancouver, Canada, Center for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Institute, University of British Columbia, Vancouver, Canada

Mohsen Sadatsafavi

Affiliations Institute for Heart and Lung Health (IHLH), Faculty of Medicine, University of British Columbia, Vancouver, Canada, Center for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Institute, University of British Columbia, Vancouver, Canada, Respiratory Medicine Division, Faculty of Medicine, University of British Columbia, Vancouver, Canada

Carlo A. Marra

Affiliation School of Pharmacy, Memorial University of Newfoundland, St. John's, Canada

Wenjia Chen

Affiliation Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada

J. Mark FitzGerald

Affiliations Institute for Heart and Lung Health (IHLH), Faculty of Medicine, University of British Columbia, Vancouver, Canada, Center for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Institute, University of British Columbia, Vancouver, Canada, Respiratory Medicine Division, Faculty of Medicine, University of British Columbia, Vancouver, Canada

Competing Interests

The authors have the following interests: J. Mark FitzGerald received a grant from Allergen. His relevant financial activities outside of the present work are from GlaxoSmithKline, AstraZeneca, Novartis, Pfizer, Boehringer-Ingelheim, Altana, Merck, and Topigen. Carlo A. Marra's relevant financial activities outside of the present work are from GlaxoSmithKline, Pfizer, Boehringer-Ingelheim, and Abbvie. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: ZZ MS CAM JMF. Performed the experiments: ZZ MS WC. Analyzed the data: ZZ. Contributed reagents/materials/analysis tools: ZZ MS. Wrote the paper: ZZ MS CAM WC JMF.