About the Authors
- Keisuke Izumi
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* E-mail: izz@keio.jp
Affiliations Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan
- Yuko Kaneko
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Affiliation Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
- Misato Hashizume
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Affiliation Product Research Department, Fuji-Gotemba Research Laboratories, Chugai Pharmaceutical Co., Ltd., Gotemba, Japan
- Keiko Yoshimoto
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Affiliation Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
- Tsutomu Takeuchi
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Affiliation Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
Competing Interests
KI, KY, and YK declare that they have no competing interests. MH is an employee of Chugai Pharmaceutical Co, Ltd. TT has received grants from Astellas Pharma Inc, Bristol-Myers KK, Chugai Pharmaceutical Co, Ltd, Daiichi Sankyo Co, Ltd, Eisai Co, Ltd, Mitsubishi Tanabe Pharma Corp, Pfizer Japan, Santen Pharmaceutical Co, Ltd, Takeda Pharmaceutical Co, Ltd, Teijin Pharma Ltd, AbbVie GK, Asahi Kasei Pharma Corp, Taisho Toyama Pharmaceutical Co, Ltd, and SymBio Pharmaceuticals Ltd; speaking fees from AbbVie GK, Bristol-Myers KK, Chugai Pharmaceutical Co, Ltd, Eisai Co, Ltd, Janssen Pharmaceutical KK, Mitsubishi Tanabe Pharma Corp, Pfizer Japan Inc, Takeda Pharmaceutical Co, Ltd, Astellas Pharma Inc, and Daiichi Sankyo Co, Ltd; and consultant fees from Astra Zeneca KK, Eli Lilly Japan KK, Novartis Pharma KK, Mitsubishi Tanabe Pharma Corp, Asahi Kasei Medical Co, Ltd, AbbVie GK, Daiichi Sankyo Co, Ltd, and Bristol-Myers KK. All of the authors declare that they have no non-financial conflicts of interest. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: KI YK TT. Performed the experiments: KI MH KY. Analyzed the data: KI YK MH TT. Wrote the paper: KI. Drafting the manuscript: KI YK MH KY TT.