About the Authors

Ruoxing Yu

Affiliation Department of Developmental and Regenerative Biology, Medical Research Institute (MRI), Tokyo Medical and Dental University (TMDU), Tokyo, 113–8510, Japan

Norio Miyamura

Affiliation Department of Developmental and Regenerative Biology, Medical Research Institute (MRI), Tokyo Medical and Dental University (TMDU), Tokyo, 113–8510, Japan

Yoshimi Okamoto-Uchida

Affiliation Department of Developmental and Regenerative Biology, Medical Research Institute (MRI), Tokyo Medical and Dental University (TMDU), Tokyo, 113–8510, Japan

Norie Arima

Affiliation Department of Developmental and Regenerative Biology, Medical Research Institute (MRI), Tokyo Medical and Dental University (TMDU), Tokyo, 113–8510, Japan

Mari Ishigami-Yuasa

Affiliation Chemical Biology Screening Center, and Department of Organic and Medicinal Chemistry, Institute of Biomaterials and Bioengineering, TMDU, Tokyo, 101–0062, Japan

Hiroyuki Kagechika

Affiliation Chemical Biology Screening Center, and Department of Organic and Medicinal Chemistry, Institute of Biomaterials and Bioengineering, TMDU, Tokyo, 101–0062, Japan

Hiroshi Nishina

nishina.dbio@mri.tmd.ac.jp

Affiliation Department of Developmental and Regenerative Biology, Medical Research Institute (MRI), Tokyo Medical and Dental University (TMDU), Tokyo, 113–8510, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RY HN. Performed the experiments: RY NM YO-U NA MI-Y. Analyzed the data: RY NM HN. Contributed reagents/materials/analysis tools: MI-Y HK HN. Wrote the paper: RY HN.