About the Authors
- Inês P. Perpétuo
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Contributed equally to this work with: Inês P. Perpétuo, Rita Raposeiro
* E-mail: ines.perpetuo@gmail.com
Affiliation Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon Academic Medical Centre, Lisboa, Portugal
- Rita Raposeiro
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Contributed equally to this work with: Inês P. Perpétuo, Rita Raposeiro
Affiliation Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon Academic Medical Centre, Lisboa, Portugal
- Joana Caetano-Lopes
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Affiliation Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon Academic Medical Centre, Lisboa, Portugal
- Elsa Vieira-Sousa
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Affiliations Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon Academic Medical Centre, Lisboa, Portugal, Rheumatology and bone metabolic diseases department, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, EPE, Lisbon Academic Medical Centre, Lisboa, Portugal
- Raquel Campanilho-Marques
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Affiliations Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon Academic Medical Centre, Lisboa, Portugal, Rheumatology and bone metabolic diseases department, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, EPE, Lisbon Academic Medical Centre, Lisboa, Portugal
- Cristina Ponte
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Affiliations Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon Academic Medical Centre, Lisboa, Portugal, Rheumatology and bone metabolic diseases department, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, EPE, Lisbon Academic Medical Centre, Lisboa, Portugal
- Helena Canhão
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Affiliations Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon Academic Medical Centre, Lisboa, Portugal, Rheumatology and bone metabolic diseases department, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, EPE, Lisbon Academic Medical Centre, Lisboa, Portugal
- Mari Ainola
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Affiliation Musculoskeletal Diseases and Inflammation Research Group, Biomedicum Helsinki, Faculty of Medicine, Institute of Clinical Medicine, University of Helsinki, Helsinki, Finland
- João E. Fonseca
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Affiliations Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon Academic Medical Centre, Lisboa, Portugal, Rheumatology and bone metabolic diseases department, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, EPE, Lisbon Academic Medical Centre, Lisboa, Portugal
Competing Interests
This work was supported by Fundação para a Ciência e Tecnologia PhD grant for the first author's salary (SFRH/BD/70533/2010) and in part by a research grant from Investigator- Initiated Studies Program of Merck Sharp & Dohme Corp (Merck_P08574). Funding from Merck Sharp & Dohme Corp was used to purchase reagents and laboratory consumables only and was not used for employees’ salary, consultancy, patents or any products in development. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials. The opinions expressed in this paper are those of the authors and do not necessarily represent those of Merck Sharp & Dohme Corp. The funding agencies had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The authors declare no conflict of interests.
Author Contributions
Conceived and designed the experiments: IPP JC JEF HC MA. Performed the experiments: IPP RR JC. Analyzed the data: IPP RR JC RC CP ES. Contributed reagents/materials/analysis tools: IPP RR RC CP ES HC. Wrote the paper: IPP RR JC RC CP ES HC MA JEF.