About the Authors

Robert C. Barber

Contributed equally to this work with: Robert C. Barber, Nicole R. Phillips, Jeffrey L. Tilson, Kirk C. Wilhelmsen

Robert.barber@unthsc.edu

Affiliations Department of Molecular & Medical Genetics, University of North Texas Health Science Center, Fort Worth, Texas, United States of America, Institute for Aging and Alzheimer’s Disease Research, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

Nicole R. Phillips

Contributed equally to this work with: Robert C. Barber, Nicole R. Phillips, Jeffrey L. Tilson, Kirk C. Wilhelmsen

Affiliation Department of Biology, University of Dallas, Dallas, Texas, United States of America

Jeffrey L. Tilson

Contributed equally to this work with: Robert C. Barber, Nicole R. Phillips, Jeffrey L. Tilson, Kirk C. Wilhelmsen

Affiliation Renaissance Computing Institute, University of North Carolina, Chapel Hill, North Carolina, United States of America

Ryan M. Huebinger

Affiliation Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Shantanu J. Shewale

Affiliation Department of Molecular & Medical Genetics, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

Jessica L. Koenig

Affiliation Department of Molecular & Medical Genetics, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

Jeffrey S. Mitchel

Affiliation Department of Molecular & Medical Genetics, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

Sid E. O’Bryant

Affiliations Institute for Aging and Alzheimer’s Disease Research, University of North Texas Health Science Center, Fort Worth, Texas, United States of America, Department of Internal Medicine, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

Stephen C. Waring

Affiliation Essentia Institute of Rural Health, Duluth, Minnesota, United States of America

Ramon Diaz-Arrastia

Affiliation Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Rockville, Maryland, United States of America

Scott Chasse

Affiliation Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America

Kirk C. Wilhelmsen

Contributed equally to this work with: Robert C. Barber, Nicole R. Phillips, Jeffrey L. Tilson, Kirk C. Wilhelmsen

Affiliations Renaissance Computing Institute, University of North Carolina, Chapel Hill, North Carolina, United States of America, Department of Genetic Medicine, University of North Carolina, Chapel Hill, North Carolina, United States of America

for the Alzheimer’s Disease Neuroimaging Initiative and the Texas Alzheimer’s Research and Care Consortium

A complete listing of ADNI and TARCC investigators can be found in the Acknowledgments.

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KCW RCB RDA SCW. Performed the experiments: KCW JLT SC RMH. Analyzed the data: KCW RCB NRP JLT JSM SJS JLK. Contributed reagents/materials/analysis tools: KCW RMH SEO. Wrote the paper: RCB KCW JLT NRP RMH.