About the Authors

Farhat Khan

Contributed equally to this work with: Farhat Khan, Mike Porter

Affiliation Structural Vaccinology Laboratory, Malaria Vaccine Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, United States of America

Mike Porter

Contributed equally to this work with: Farhat Khan, Mike Porter

Affiliation Structural Vaccinology Laboratory, Malaria Vaccine Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, United States of America

Robert Schwenk

Affiliation Structural Vaccinology Laboratory, Malaria Vaccine Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, United States of America

Margot DeBot

Affiliation Structural Vaccinology Laboratory, Malaria Vaccine Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, United States of America

Philippe Saudan

Affiliation Cytos Biotechnology, Wagistrasse 25, 8952 Schlieren, Switzerland

Sheetij Dutta

Sheetij.dutta.civ@mail.mil

Affiliation Structural Vaccinology Laboratory, Malaria Vaccine Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, United States of America

Competing Interests

SD has a patent on the CS protein described in this manuscript (Title: Plasmodium falciparum circumsporozoite vaccine gene optimization for soluble protein expression; patent # 9,115,205). PS is affiliated to a commercial entity Cytos Biotechnology. PS was an active participant throughout this study and during manuscript preparation. The commercial affiliation of PS did not in any way affect the conduct of the study. None of the above mentioned interests have altered the authors' adherence to all PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SD PS. Performed the experiments: FK MP RS MD. Analyzed the data: FK MP RS MD SD PS. Wrote the paper: SD PS.