About the Authors

Luisa Lanzilao

Contributed equally to this work with: Luisa Lanzilao, Giuseppe Stefanetti

Affiliation Sclavo Behring Vaccines Institute for Global Health S.r.l., a GSK company (formerly Novartis Vaccines Institute for Global Health S.r.l), Via Fiorentina 1, 53100, Siena, Italy

Giuseppe Stefanetti

Contributed equally to this work with: Luisa Lanzilao, Giuseppe Stefanetti

Affiliation Sclavo Behring Vaccines Institute for Global Health S.r.l., a GSK company (formerly Novartis Vaccines Institute for Global Health S.r.l), Via Fiorentina 1, 53100, Siena, Italy

Allan Saul

Affiliation Sclavo Behring Vaccines Institute for Global Health S.r.l., a GSK company (formerly Novartis Vaccines Institute for Global Health S.r.l), Via Fiorentina 1, 53100, Siena, Italy

Calman A. MacLennan

Affiliations Jenner Institute, Nuffield Department of Medicine, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, United Kingdom, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdom

Francesca Micoli

Affiliation Sclavo Behring Vaccines Institute for Global Health S.r.l., a GSK company (formerly Novartis Vaccines Institute for Global Health S.r.l), Via Fiorentina 1, 53100, Siena, Italy

Simona Rondini

simona.x.rondini@gsk.com

Affiliation Sclavo Behring Vaccines Institute for Global Health S.r.l., a GSK company (formerly Novartis Vaccines Institute for Global Health S.r.l), Via Fiorentina 1, 53100, Siena, Italy

Competing Interests

Luisa Lanzilao, Giuseppe Stefanetti, Allan Saul, Calman A. MacLennan, Francesca Micoli and Simona Rondini were employees of Novartis Vaccines Institute for Global Health S.r.l. at the time the study was conducted; all of the preceding listed authors, except Giuseppe Stefanetti and Calman A. MacLennan, are now employees of Sclavo Behring Vaccines Institute For Global Health S.r.l., a GSK Company, Siena, Italy. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GS LL FM SR AS CM. Performed the experiments: LL GS FM SR. Analyzed the data: GS LL FM SR CM AS. Contributed reagents/materials/analysis tools: LL GS FM SR. Wrote the paper: FM SR GS LL AS CM.